ARTHRITIS

Joint pain that won't go away no matter what you do
Have you given up, thinking, "It might stay like this forever?"

Conventional treatments focus on symptomatic treatment with painkillers and anti-inflammatory drugs.
However, these treatments have limitations:

  • Taking medicines doesn't really improve the condition
  • Recurring symptoms
  • Concerns about side effects from long-term use

It is for people like this that we want them to know about the true cause of chronic inflammation and new options available through regenerative medicine.

Do you have any concerns?
issues like these?

  • Stiffness in the joints when waking up in the morning
  • Knee pain when going up and down stairs
  • Unable to sit upright, and crouching is painful
  • It's getting hard to go shopping
  • Giving up on favorite exercise or hobbies
  • The good days don't continue
    (I can't enjoy concerts or theater)
  • Bad weather makes my joints hurt
  • Pain that doesn't go away even after taking medicine
  • I don't want surgery, but I don't see any other options.

If any of these apply to you, please feel free to contact us.

There are various types of arthritis, including osteoarthritis, rheumatoid arthritis, gout/pseudogout, and septic arthritis, but what they all have in common is the reaction called "inflammation."

Why does arthritis become chronic?

The root cause of chronic joint pain is chronic inflammation.
In a healthy body, when joint pain occurs, the body naturally repairs itself through the following process:

The repair process from the onset of arthritis to the resolution of pain

  1. Inflammation occurs(Indicate the damaged area)
  2. Stops bleeding(Platelets seal the wound)
  3. Macrophages
    Broken cells and bacteria
    Clean up
  4. Macrophages
    From cleaning to repairing
    Switch to a helping role
  1. This is importantStem cells
    Create a new organization
    (Stem cells gather from various places)
  2. Cells cooperate with each other(Information exchange through exosomes)
  3. Completely healed(Tissue regeneration completed)

However, if chronic inflammation continues, this repair process stops at the fourth stage.

At this time, macrophages, immune cells in the body, become important.
Macrophages typically perform the following functions:

The two roles of macrophages

role 1

Cleaner

Removes bacteria and broken cells from inflamed areas

role 2

Restoration Support

Promotes tissue repair and supports stem cell mobilization

This "switching" of roles is key to the body's ability to heal properly.

However, when chronic inflammation continues, macrophages remain in their cleaning role and do not switch over to assist in repair, which results in stem cells (cells that regenerate tissue) not functioning properly and preventing the tissues in the lower back from repairing.

This is the real cause of "arthritis that won't go away no matter what you do."

Conventional treatments (painkillers, compresses, injections, etc.) do not address the underlying cause of chronic inflammation, so even if they temporarily relieve pain, the same symptoms will recur.

"Cell Revival®" targets
Symptoms and diseases

The body is naturally equipped with an amazing recovery mechanism, but as chronic inflammation progresses due to various external factors such as aging and lifestyle habits, this mechanism weakens.

Cell Revival® is a treatment method unique to our hospital that combines three regenerative medical therapies. By gradually combining macrophage therapy, stem cell therapy, PRP therapy, and iPS exosome therapy, we maximize the therapeutic effect.

First, we accurately assess the body's condition and create a repair environment within the body before beginning stem cell therapy. This fundamental approach maximizes the body's innate ability to recover.

PHASES

Stage 1

Visualizing chronic inflammation

  • Inflammation levels are quantified using inflammatory marker tests (high-sensitivity CRP, IL-1β, IL-6, TNFα)
  • EpiClock test measures the effects of inflammation on cells
  • Developing a treatment plan based on objective data
Stage 2

In macrophages
Creating a recovery environment

  • Calms chronic inflammation
  • Creating a work environment that is conducive to regenerative medicine
Stage 3

Stem cell therapy for recovery
Facilitate

  • Stem cells are administered into a controlled environment
  • If necessary, PRP therapy and iPS exosome therapy may be used in combination.

DISEASE

Orthopedics and joint diseases

Gynecological and endocrine disorders

  • Menopause

    Improves symptoms by adjusting hormone balance and suppressing chronic inflammation

  • infertility

    Improve ovarian function, repair endometrial lining, and improve the body's ability to become pregnant

Sequelae of infectious diseases and immune disorders

  • Corona aftereffects

    Suppresses inflammation throughout the body, normalizes immune function, and improves fatigue and shortness of breath

  • Chronic fatigue syndrome

    Improved energy production at the cellular level, alleviating symptoms

Internal medicine/metabolic diseases

  • Diabetes mellitus

    Improved pancreatic beta cell function and blood sugar control

  • Liver disease

    Regeneration of liver cells and recovery of liver function

  • Kidney disease

    Protecting and improving kidney function

Nervous system disorders

  • Stroke sequelae

    Regeneration of nerve cells, improvement of paralysis and numbness

  • Spinal cord injury

    Recovery of nerve function, improvement of motor function

  • Parkinson's disease

    Neuroprotection, suppression of symptom progression

cardiovascular disease

  • Myocardial infarction

    Regeneration of cardiomyocytes and improvement of cardiac function

  • peripheral arterial disease

    Angiogenesis, blood flow improvement

Beauty and Anti-Aging

  • Skin regeneration

    Promotes collagen production and improves wrinkles and sagging

  • hair regeneration

    Activation of hair follicles and promotion of hair growth

  • whole body anti aging

    Rejuvenation at the cellular level

*Effects vary from person to person. Appropriateness will be determined through a medical examination.

FLOW

STEP
1

Detailed examination and testing

  • Check the detailed condition of the symptoms and receive medical examination
  • Inflammation levels are measured using inflammatory marker tests (high-sensitivity CRP, IL-1β, IL-6, TNFα)
  • EpiClock test measures the effects of inflammation on cells
  • Determining treatment suitability
STEP
2

Pretreatment (macrophage treatment)

  • Improves chronic inflammation
  • Improving the restoration environment
  • Creating a foundation where stem cells can function
STEP
3

Stem cell collection and culture

  • Stem cells are extracted from adipose tissue and bone marrow
  • Cultivation and quality control in a dedicated clean room
  • Only cells that meet strict standards are used
STEP
4

Treatment implementation

  • Select the most appropriate administration method depending on the symptoms and area (intra-articular injection, intravenous drip, local injection, etc.)
  • Combination treatment with our unique "Cell Revival®"
STEP
5

Long-term follow-up

  • Up to two years of continuous support
  • Effect measured through regular blood tests
  • Consider additional treatment if necessary

FAQ

  • Does regenerative medicine for arthritis really work? How does it differ from other treatments?

    Unlike conventional symptomatic treatments, Cell Revival® is a treatment that addresses the root cause of chronic inflammation.

    Differences from conventional treatment:
    - Painkillers and compresses: only temporarily suppress symptoms
    - Hyaluronic acid injections: Provides lubrication to joints but does not repair tissue
    - Surgery: requires hospitalization and places a heavy burden on the body
    - Cell Revival®: Improves chronic inflammation and regenerates tissue. Treatment can be performed on an outpatient basis, no hospitalization required.

    At our clinic, we use inflammatory marker tests to quantify the effects and objectively confirm improvement. Most patients improve their joints within 3-6 months.
    They have experienced improved movement and reduced pain.

  • How long will the treatment take? Will I need to take time off work?

    Estimated treatment period: - Initial examination and consultation: 1 day - Macrophage therapy (pretreatment): 2-4 weeks - Stem cell culture: 3-4 weeks - Total: Approximately 2-3 months Impact on work: - At the time of collection: Local anesthesia is used, and normal activities can be carried out from the same day - After treatment: No hospitalization required, and patients can return to work the next day - Regular visits to the hospital: Approximately 1-2 times a month Many patients continue working while receiving treatment.

  • Are there any age restrictions? Can elderly people receive treatment?

    Cell Revival® has no upper age limit, as long as you are over 20 years old. There is also a proven track record of treating many people over 80 years old. Consideration for the elderly: - Cell function is restored regardless of age using culture technology - Treatment methods that place less strain on the body are selected - Treatment plans tailored to each individual's physical strength In fact, the older you are, the more advanced your chronic inflammation becomes, so you tend to be more likely to feel the effects of Cell Revival®.

  • Are there any side effects or risks? Is it safe?

    Cell Revival® is a safe treatment that uses your own cells, with an extremely low risk of rejection. Our commitment to safety: - Only cells that meet strict quality control standards are used - Cells are processed in a clean bench using specialized devices to prevent bacterial contamination - A team medical system with specialists in various fields - Safety is confirmed in advance through cancer cell testing Minor side effects: - Temporary swelling and pain at the extraction site - Mild swelling at the injection site (resolves in 2-3 days) No serious side effects have been reported.

  • Is insurance applicable? What is the approximate cost of treatment?

    Unfortunately, regenerative medicine is currently not covered by insurance and is therefore not an option. Regarding costs: - Varies depending on symptoms and scope of treatment - Detailed estimates will be provided during the initial consultation (3,500 yen) - Installment payment options are also available. Regarding medical expense deductions: - Annual medical expenses over 10 yen can be deducted through tax returns - Treatment costs, testing costs, and transportation costs to hospitals are also covered - Please keep receipts safe. We will first propose a treatment plan tailored to your symptoms via a free email consultation. *Please consult with a tax accountant for details.

Clinic Le GINZA
5 features

Treating aging as a therapeutic target
New regenerative medicine

The aim is to scientifically measure and improve chronic inflammation, a treatable cause of ailments that have traditionally been attributed to aging (an approach to scientifically diagnosing and treating aging).

by specialists in each field
"Team medical care" system

Orthopedic, gynecological, and internal medicine doctors work together to create treatment plans optimized for each patient's condition.

Maximize the body's natural ability to recover
"Cell Revival®"

A unique three-step treatment that improves chronic inflammation and prepares the foundation for stem cell therapy

Based on scientific data
Effect verification

Inflammatory marker testing and EpiClock testing confirm improvement through data, not just feelings

Rest assured even after treatment
Long-term follow-up

Regular checkups and support for up to two years will help maintain and further improve the effectiveness of treatment.

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