CELL REVIVAL Cell Revival®

*Trademark registration pending (Trademark Application No. 2025-110505)

Combining three regenerative medical treatments to restore the body's natural ability to recover

The body is naturally equipped with an amazing recovery mechanism, but as chronic inflammation progresses due to various external factors such as aging and lifestyle habits, this mechanism weakens.

Cell Revival® is a treatment method unique to our hospital that combines three regenerative medical therapies. By gradually combining macrophage therapy, stem cell therapy, PRP therapy, and iPS exosome therapy, we maximize the therapeutic effect.

First, we accurately assess the body's condition and create a repair environment within the body before administering stem cell therapy. This fundamental approach maximizes the body's innate ability to recover.

STEP

STEP1

Visualizing chronic inflammation

1Chronic Inflammation Test

Asymptomatic inflammation in the body is comprehensively evaluated using four indicators.

High sensitivity CRP

Systemic inflammation levels
IL-6

Causes of fatigue and muscle weakness
TNFα

Degree of tissue destruction
IL-1β

Inflammatory activity

By comparing with normal values, we can clarify where the problem is and develop the optimal treatment plan.

2Epiclock test

This test measures the effects of inflammation on cells at the genetic level. It evaluates the genetic state of cells and measures the degree of cellular aging.

Example: Age 55 → Biological age 62 (case of accelerated aging due to chronic inflammation)

STEP2

Laying the foundation for recovery with macrophages

The body naturally has the ability to recover and heal wounds and illnesses. However, as chronic inflammation progresses due to aging and lifestyle habits, this ability weakens, making it difficult for wounds to heal and fatigue to disappear.

The key to improving this chronic inflammation is immune cells called macrophages.
When macrophages function normally, the body's recovery ability is improved and the effects of regenerative medicine are maximized.

However, as chronic inflammation continues, the function of macrophages weakens, undermining the foundation for recovery.

Our clinic is the only one in Japan that offers "macrophage therapy." We restore the function of weakened macrophages and control chronic inflammation. This prepares the body for regenerative medicine to work effectively.

Once this foundation is in place, the next step, Step 3, of treatment will be more effective.

What is macrophage therapy?

STEP3

Unlocking recovery potential with stem cell therapy

Once the internal environment is prepared in STEP 2, the stem cells are finally administered.

Stem cells are "pluripotent cells" that can transform into a variety of tissues as needed, such as bone, cartilage, muscle, and blood vessels. They find and gather at injured areas (homing effect), transform into new cells, and promote tissue recovery.

At our hospital, stem cells are extracted from your own fat tissue and then cultured and activated in a dedicated clean room. Because we ensure a sufficient number of cells before administering them, the procedure is highly safe and there is little risk of rejection.

In addition, PRP therapy and iPS exosome therapy can be used in combination depending on the symptoms and purpose. Exosomes are substances that transmit information between cells, and by delivering information from young cells, they boost the body's ability to recover.

On the foundation established by macrophage therapy, stem cells and exosomes exert a synergistic effect, aiming to improve symptoms that have been difficult to treat until now.

What is stem cell therapy? What is iPS exosome therapy?

DISEASE "Cell Revival®" targets
Symptoms and diseases

Orthopedics and joint diseases

Low back pain
arthritis
Spinal canal stenosis
Osteoarthritis of the knee
Meniscus damage
Coxarthrosis

Gynecological and endocrine disorders

Menopause

Improves symptoms by adjusting hormone balance and suppressing chronic inflammation
infertility

Improve ovarian function, repair endometrial lining, and improve the body's ability to become pregnant

Sequelae of infectious diseases and immune disorders

Corona aftereffects

Suppresses inflammation throughout the body, normalizes immune function, and improves fatigue and shortness of breath
Chronic fatigue syndrome

Improved energy production at the cellular level, alleviating symptoms

Internal medicine/metabolic diseases

Diabetes mellitus

Improved pancreatic beta cell function and blood sugar control
Liver disease

Regeneration of liver cells and recovery of liver function
Kidney disease

Protecting and improving kidney function

Nervous system disorders

Stroke sequelae

Regeneration of nerve cells, improvement of paralysis and numbness
Spinal cord injury

Recovery of nerve function, improvement of motor function
Parkinson's disease

Neuroprotection, suppression of symptom progression

cardiovascular disease

Myocardial infarction

Regeneration of cardiomyocytes and improvement of cardiac function
peripheral arterial disease

Angiogenesis, blood flow improvement

Beauty and Anti-Aging

Skin regeneration

Promotes collagen production and improves wrinkles and sagging
hair regeneration

Activation of hair follicles and promotion of hair growth
whole body anti aging

Rejuvenation at the cellular level

*Effects vary from person to person. Appropriateness will be determined through a medical examination.

FLOW Treatment flow

STEP

Detailed examination and testing

Check the detailed condition of the symptoms and receive medical examination
Inflammation levels are measured using inflammatory marker tests (high-sensitivity CRP, IL-1β, IL-6, TNFα)
EpiClock test measures the effects of inflammation on cells
Determining treatment suitability

STEP

Pretreatment (macrophage treatment)

Improves chronic inflammation
Improving the restoration environment
Creating a foundation where stem cells can function

STEP

Stem cell collection and culture

Stem cells are extracted from adipose tissue and bone marrow
Cultivation and quality control in a dedicated clean room
Only cells that meet strict standards are used

STEP

Treatment implementation

Select the most appropriate administration method depending on the symptoms and area (intra-articular injection, intravenous drip, local injection, etc.)
Combination treatment with our unique "Cell Revival®"

STEP

Long-term follow-up

Up to two years of continuous support
Effect measured through regular blood tests
Consider additional treatment if necessary

FAQ Frequently Asked Questions

How is Cell Revival® different from other regenerative medicines?

The greatest feature of Cell Revival® is that it combines the necessary treatments. Many regenerative medicines simply administer stem cells, but stem cells cannot function adequately in conditions of chronic inflammation. Our clinic uses Japan's only macrophage therapy, which first improves chronic inflammation and creates a foundation for stem cells to exert their maximum effect. This three-step approach (examination → pretreatment → treatment) promises to produce a higher therapeutic effect than conventional regenerative medicine.
How long will the treatment take? What is the estimated cost?

The treatment period varies depending on the symptoms, but the general procedure is as follows: Initial consultation and examination: 1 day (starting from approximately 1 hour), macrophage therapy (pre-treatment): 2-4 weeks, stem cell culture: 3-4 weeks, treatment: 1 day (approximately 1 hour), total: approximately 2-3 months. After that, follow-up will be conducted for up to 2 years while monitoring the condition. Regarding costs: As costs vary depending on the symptoms and scope of treatment, a detailed estimate will be provided during counseling (initial consultation fee: 3,500 yen). We also accept inquiries about installment payments.
What symptoms is it effective for? Can it treat my symptoms?

Cell Revival® can treat a wide range of symptoms. Symptoms for which it is particularly effective include joint pain (knee osteoarthritis, lower back pain, arthritis, etc.), menopausal symptoms (hot flashes, fatigue, depression), chronic fatigue (fatigue of unknown cause), lifestyle-related diseases (diabetes, decreased liver function), and beauty concerns (sagging skin, thinning hair). First, we conduct a chronic inflammation test to accurately understand the condition of your body and determine whether treatment is appropriate. Symptoms that you have given up on, believing they are just due to aging, may actually be caused by chronic inflammation.
Are there any side effects or risks? Is it safe?

Cell Revival® is a safe treatment that uses your own cells, with an extremely low risk of rejection. Safety initiatives: - Only cells that meet strict quality control standards are used - Cultivation in a dedicated clean room - A team medical system with specialists in various fields - Detailed testing before treatment to determine suitability Minor side effects: - Temporary swelling and pain at the injection site - Mild feeling of heat (resolves in 1-2 days) No serious side effects have been reported, but if any do occur, specialists will respond promptly.
How long after treatment will I see results? Do the results last?

While the time it takes to see results varies depending on the symptoms, many patients experience the following progression: 2-4 weeks after treatment: reduced fatigue and improved sleep quality; 1-2 months: reduced joint pain and improved skin quality; 3-6 months: clear improvement in chronic symptoms. Because macrophage therapy regulates the internal environment, the effects tend to last longer than with conventional regenerative medicine. Furthermore, we aim to maintain and improve the effects by regularly measuring inflammatory markers over a maximum follow-up period of two years and considering additional treatments as needed. We also provide guidance on lifestyle changes to help maximize and sustain the effects of treatment.

View Frequently Asked Questions and Answers

Clinic Le GINZA
5 features

Treating aging as a therapeutic target
New regenerative medicine

The aim is to scientifically measure and improve chronic inflammation, a treatable cause of ailments that have traditionally been attributed to aging (an approach to scientifically diagnosing and treating aging).