STEM CELL Stem cell therapy
Fundamental treatment that maximizes the body's natural recovery ability
The body is naturally endowed with the ability to heal itself, or recover. However, as chronic inflammation progresses due to aging and lifestyle habits, this ability gradually declines.
Stem cell therapy is a regenerative medicine that aims to restore this lost recovery ability. It is not just a symptomatic treatment that suppresses symptoms, but promotes regeneration from within the body, aiming to restore a healthy state.
What are stem cells?
Stem cells are special cells that are naturally present in our bodies and can also be called "pluripotent cells."
These cells have two amazing abilities.
These two functions allow stem cells to gather in injured areas of the body, generating new tissue and supporting recovery.
For example, the natural healing of skin wounds and the restoration of broken bones are all thanks to the daily activity of stem cells.
self-replication ability
The power to infinitely increase stem cells that are exactly the same as your own.
multipotent
The ability to transform into various cells throughout the body, such as bone, cartilage, muscle, blood vessels, and nerves.
Unfortunately, as we age, the number of stem cells in our bodies decreases and their power weakens.
The number of stem cells declines rapidly with age, dropping to approximately 1/200 of that of a newborn by age 80. This decline, combined with the progression of chronic inflammation, significantly reduces the body's ability to recover.
Although the number of stem cells decreases with age, cell function can be restored and improved using culture techniques.
During the culture process, the collected stem cells are grown in a specialized environment to increase their activity and restore their original functions. Even cells from older individuals can be expected to be sufficiently effective with proper culture, so patients can receive treatment with peace of mind.
What is stem cell therapy?
Stem cell therapy is a treatment that compensates for the body's reduced ability to recover and promotes the regeneration of damaged tissue by cultivating and increasing the number of stem cells collected from the body and then returning them to the body.
See the stages of stem cell therapy
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Stage1 Regenerates damaged tissue
In areas such as worn cartilage, intervertebral discs, and weakened muscles, stem cells transform into the necessary cells to support recovery.
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Stage2 Calms chronic inflammation
It suppresses chronic inflammation that causes pain and discomfort, and brings out the body's natural ability to recover.
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Stage3 Improves blood flow
Creating new blood vessels improves the supply of oxygen and nutrients, speeding up healing.
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Stage4 Balance the immune system
It can regulate over-reacting immune systems and may also improve autoimmune diseases.
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Stage5 Activates surrounding cells
The special substances secreted by stem cells invigorate surrounding cells, creating a synergistic effect.
Three fundamental problems with conventional stem cell therapy
Currently, stem cell therapy is widely performed by returning cultured stem cells to the body.
This method has also contributed to the improvement of many symptoms, but recent research and clinical experience have revealed challenges to further improve the treatment's effectiveness.
ISSUE
Misconceptions about the role of stem cells
In previous stem cell therapy, it was thought that injected stem cells directly treated the disease. However, in reality, treatment involves not only the injected cells, but also cells that are already present in the body. Therefore, it is necessary to change the cells used and the method of administration according to the state of the body.
The environment for stem cells to work is not suitable
Stem cells alone are not sufficient for tissue recovery. It is important that immune cells called "macrophages" first clean up damaged cells and create an environment conducive to recovery. Conventional treatments do not fully utilize the functions of these "macrophages," which can prevent stem cells from fully exerting their inherent restorative powers.
The effectiveness of treatment cannot be objectively confirmed
In conventional treatments, there are no clear standards for quantifying changes in recovery, so evaluation tends to be based solely on the patient's perception. This can lead to concerns such as "Are there really improvements?" and "Are the treatments producing results worth the effort?"
Our unique treatment, "Cell Revival®," solves all three problems.
The body is naturally equipped with an amazing recovery mechanism, but as chronic inflammation progresses due to various external factors such as aging and lifestyle habits, this mechanism weakens.
Cell Revival® is a treatment method unique to our hospital that combines three regenerative medical therapies. By gradually combining macrophage therapy, stem cell therapy, PRP therapy, and iPS exosome therapy, we maximize the therapeutic effect.
First, we accurately assess the current condition and create a repair environment within the body before starting stem cell therapy. This fundamental approach maximizes the body's natural ability to recover.
PHASES
Visualizing chronic inflammation
- Inflammation levels are quantified using inflammatory marker tests (high-sensitivity CRP, IL-1β, IL-6, TNFα)
- EpiClock test measures the effects of inflammation on cells
- Developing a treatment plan based on objective data
In macrophages
Creating a recovery environment
- Calms chronic inflammation
- Creating a work environment that is conducive to regenerative medicine
Stem cell therapy for recovery
Facilitate
- Stem cells are administered into a controlled environment
- If necessary, PRP therapy and iPS exosome therapy may be used in combination.
DISEASE
"Cell Revival®" targets
Symptoms and diseases
Orthopedics and joint diseases
- Low back pain
- arthritis
- Spinal canal stenosis
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Osteoarthritis of the knee
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Meniscus damage
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Coxarthrosis
Gynecological and endocrine disorders
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Menopause
Improves symptoms by adjusting hormone balance and suppressing chronic inflammation
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infertility
Improve ovarian function, repair endometrial lining, and improve the body's ability to become pregnant
Sequelae of infectious diseases and immune disorders
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Corona aftereffects
Suppresses inflammation throughout the body, normalizes immune function, and improves fatigue and shortness of breath
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Chronic fatigue syndrome
Improved energy production at the cellular level, alleviating symptoms
Internal medicine/metabolic diseases
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Diabetes mellitus
Improved pancreatic beta cell function and blood sugar control
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Liver disease
Regeneration of liver cells and recovery of liver function
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Kidney disease
Protecting and improving kidney function
Nervous system disorders
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Stroke sequelae
Regeneration of nerve cells, improvement of paralysis and numbness
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Spinal cord injury
Recovery of nerve function, improvement of motor function
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Parkinson's disease
Neuroprotection, suppression of symptom progression
cardiovascular disease
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Myocardial infarction
Regeneration of cardiomyocytes and improvement of cardiac function
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peripheral arterial disease
Angiogenesis, blood flow improvement
Beauty and Anti-Aging
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Skin regeneration
Promotes collagen production and improves wrinkles and sagging
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hair regeneration
Activation of hair follicles and promotion of hair growth
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whole body anti aging
Rejuvenation at the cellular level
*Effects vary from person to person. Appropriateness will be determined through a medical examination.
FLOW Treatment flow
Detailed examination and testing
- Check the detailed condition of the symptoms and receive medical examination
- Inflammation levels are measured using inflammatory marker tests (high-sensitivity CRP, IL-1β, IL-6, TNFα)
- EpiClock test measures the effects of inflammation on cells
- Determining treatment suitability
Pretreatment (macrophage treatment)
- Improves chronic inflammation
- Improving the restoration environment
- Creating a foundation where stem cells can function
Stem cell collection and culture
- Stem cells are extracted from adipose tissue and bone marrow
- Cultivation and quality control in a dedicated clean room
- Only cells that meet strict standards are used
Treatment implementation
- Select the most appropriate administration method depending on the symptoms and area (intra-articular injection, intravenous drip, local injection, etc.)
- Combination treatment with our unique "Cell Revival®"
Long-term follow-up
- Up to two years of continuous support
- Effect measured through regular blood tests
- Consider additional treatment if necessary
FAQ Frequently Asked Questions
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Can anyone receive stem cell therapy? Are there any age restrictions?
Stem cell therapy can generally be performed on anyone over the age of 20. There is also a history of treatment on people over the age of 80. However, the following people cannot undergo the treatment: those with a history of cancer (confirmed by blood test), those with a serious infection, those who are pregnant or breastfeeding, and others who a doctor deems unsuitable for the treatment. The number of stem cells decreases with age, but their function can be restored using culture techniques, so even elderly people can expect to see satisfactory results. We will first determine suitability through a detailed examination.
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Where are the stem cells collected? Is the collection process painful?
At our clinic, we collect stem cells in two main ways: 1. Collection from adipose tissue (most common) - A few grains of rice worth of fat is collected from the abdomen or thigh - Local anesthesia is used, so there is almost no pain - Collection takes approximately 20-30 minutes - Normal activities can be resumed the same day 2. Collection from the ilium (hip bone) - This is done under local anesthesia - Patients must rest after collection The method to be chosen will be determined by the doctor based on the symptoms and treatment goals.
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What is the difference between this and other stem cell treatments?
The greatest feature of our stem cell therapy is our unique three-stage treatment method called "Cell Revival®." Differences from conventional stem cell therapy: 1. Pre-treatment: Improve the internal environment with Japan's only macrophage therapy. 2. Visualization of effects: Quantify results with Epiclock testing and inflammatory marker testing. 3. Multi-disciplinary approach: Combine with PRP therapy and exosome therapy as needed. 4. Long-term follow-up: Continuous support for up to two years. By creating an environment where stem cells can function at their best before treatment, rather than simply injecting stem cells, we can expect even greater results.
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How long do the effects of treatment last? Are retreatments necessary?
The duration of effect varies from person to person, but the following progression is generally seen in many patients. Duration of effect: Effects last approximately 6 months to 2 years after the initial treatment. If chronic inflammation is improved, effects can be expected to last longer, but by combining it with lifestyle changes, effects will last even longer. Regarding retreatment: Additional treatment will be considered depending on symptoms and test results. Most patients maintain effects by receiving additional treatment around a year, and regular examinations will determine the optimal timing. At our clinic, we follow up for up to 2 years to check the durability of effects and suggest additional treatment if necessary.
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How many millions of stem cells will there be after culturing? Is it more effective if there are more?
In our hospital's infusion therapy, the standard number of stem cells used is 2 million. If the number of cells is too high, it temporarily increases the burden on the capillaries and, in the worst case, can cause shock symptoms. Stem cell therapy drugs for treating spinal cord injuries available in Japan have a maximum dose of 334 million times the patient's body weight, and the amount of cells is adjusted for safety reasons. While it may seem that a higher number of cells is better, our hospital prioritizes safe treatment for patients, and uses a standard of 2 million cells to strike a balance between safety and therapeutic effectiveness.
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Is insurance applicable? Can I receive a medical expense deduction?
Insurance Coverage: Stem cell therapy is currently not covered by insurance and is an elective medical treatment. The full cost is borne by the patient, but we are happy to discuss payment in installments. Medical Expense Deductions: Stem cell therapy may be eligible for medical expense deductions. - If your annual medical expenses exceed 10 yen, you can deduct them on your tax return. - Treatment costs, testing costs, and transportation costs to hospitals are also covered. - Please keep your receipts safe. Cost Estimate: During your initial consultation (3,500 yen), we will provide you with a detailed estimate based on your symptoms. Costs vary depending on the treatment, so please consult with us first. *For more details, please consult with a tax accountant.
Clinic Le GINZA
5 features
Treating aging as a therapeutic target
New regenerative medicine
The aim is to scientifically measure and improve chronic inflammation, a treatable cause of ailments that have traditionally been attributed to aging (an approach to scientifically diagnosing and treating aging).
by specialists in each field
"Team medical care" system
Orthopedic, gynecological, and internal medicine doctors work together to create treatment plans optimized for each patient's condition.
Maximize the body's natural ability to recover
"Cell Revival®"
A unique three-step treatment that improves chronic inflammation and prepares the foundation for stem cell therapy
Based on scientific data
Effect verification
Inflammatory marker testing and EpiClock testing confirm improvement through data, not just feelings
Rest assured even after treatment
Long-term follow-up
Regular checkups and support for up to two years will help maintain and further improve the effectiveness of treatment.
